Global WholeHealth Partners
The Science
SilverStream® products effectively & rapidly clean, moisturize, and soothe Chronic & Hard-To-Treat Wounds. Our safe, free from side effects & effective products are designed to Accelerate Natural Wound Healing Processes.
Our products are based on an innovative combination of a low concentration of silver ions, menthol, glycerol, and a surfactant, dissolved in a hypertonic solution.
The high concentration of the hygroscopic glycerol provides hydrogel effects.
SilverStream® Solution Mechanism of Action
Ingredient | Action | Description |
|---|---|---|
| Ag NO3 | Preservative & Anti-microbial agent | Ionic silver kills on contact and inhibits the growth of bacteria, yeast, and fungi |
| Menthol | Penetration enhancer Growth promoter Pain reliever Odor fighter | Enhances ionic silver antimicrobial activities and fights wound odor Promotes granulation tissue growth by vasodilatation |
| Tween 20 | Surfactant and Detergent | Enhances solution penetration into the biofilm Acts as wound cleansing detergent |
| Glycerol | A hypertonic aqueous solution that prevents macerations Soothing agent | Aids mechanical removal of exudates and microorganisms Creates Hydrogel function by absorbing water molecules |
| Tris Buffer | Buffered neutral pH | Biocompatible to physiological pH |
SilverStream® Gel Mechanism of Action
Ingredient | Action | Description |
|---|---|---|
| Ag NO3 | Preservative & Anti-microbial agent | Ionic silver kills on contact and inhibits the growth of bacteria, yeast, and fungi |
| Menthol | Penetration enhancer Growth promoter Pain reliever Odor fighter | Enhances ionic silver antimicrobial activities and fights wound odor Promotes granulation tissue growth by vasodilatation |
| Tween 20 | Surfactant and Detergent | Enhances solution penetration into the biofilm Acts as wound cleansing detergent |
| Glycerol | A hypertonic aqueous solution that prevents macerations Soothing agent | Aids mechanical removal of exudates and microorganisms Creates Hydrogel function by absorbing water molecules |
| Carbopol | Thickening agent | Extends the presence and availability of the product on the wound |
| Tris Buffer | Buffered neutral pH | Biocompatible to physiological pH |
Silver Ions induce Apoptosis
SilverStream proven to destroy Biofilms
Garth James, PhD, Center for Biofilm Engineering, Montana State University-Bozeman, 366 EPS Building, P.O. Box 173980, Bozeman, MT 59717-3980
SilverStream® Solution and SilverStream® Gel Safety
Summary of Biocompatibility Testing Conducted on SilverStream® Solution & SilverStream Gel®
Biological Effect | Results |
|---|---|
| Irritation | Non-Irritant |
| Acute Systemic Toxicity | Non-Toxic |
| Sensitization | Non-Sensitizing |
| Cytotoxicity Study ISO Direct Contact Method | Non-Cytotoxic |
| Material-mediated Pyrogenicity (rabbits) | Non-Pyrogenic (Gel only) |
| Assessment of Potential Wound Healing (swine) | Passed (Gel only) |
The Synergy between the SilverStream® Solution and SilverStream® Gel
The synergy provides Extraordinary Wound Healing Results
Recommended synergy treatment in:
- Jet debridement –Jetox De Royal, Versa-Jet (S&N)
- Negative Pressure Wound Treatment- KCI ULTA NPWT, IVT – Vcare & others
Redefining Wound Care for Professionals and Home Use
SilverStream: A Patented Breakthrough in Wound Care and Prevention
SilverStream is a patented solution that redefines wound care and prevention. With just 0.01% silver nitrate, it achieves remarkable effectiveness through the unique synergy of its carefully selected components. This low concentration ensures safety while delivering outstanding performance, making it an advanced choice for both treatment and prevention.
Not Just Silver – The Synergy Behind SilverStream Technology
SilverStream technology is much more than a silver-based solution. By integrating silver nitrate with menthol, glycerol, a surfactant, and a hypertonic environment, it harnesses a powerful synergy that enhances wound cleansing, accelerates healing, reduces bacterial load, and supports infection prevention. Its natural pH ensures it is gentle on wounds while maintaining high efficacy.
Biofilm Destruction and Infection Control
SilverStream’s advanced technology effectively disrupts biofilm, a key barrier to wound healing, while reducing bacterial load to control infection. Its unique synergy of ingredients ensures enhanced wound cleansing and accelerates the healing process, supporting optimal recovery.
Exceptional Antimicrobial and Preservative Power
SilverStream’s advanced formula delivers outstanding antimicrobial and antifungal protection, effectively targeting pathogens commonly found in wounds. As a preservative and antimicrobial agent, it demonstrates 99.99% or greater bactericidal and fungicidal efficacy, providing robust defense against infections, including those caused by resistant bacteria.
- Escherichia coli
- Staphylococcus aureus (MRSA)
- Staphylococcus epidermidis
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
- Anaerobes bacteria
- Candida albicans
- Aspergillus niger
- Trichophyton rubrum
- Microsporum canis
How SilverStream Works
SilverStream is not a silver cleanser—it’s a totally different, all-in-one synergistic wound dressing and irrigation solution that also includes silver ions.
Discover the innovative mode of action behind SilverStream Solution—designed to clean, moisturize, protect, and support an optimal environment at every stage of wound healing. Learn how its unique formula of antimicrobial silver ions, menthol, glycerol, and surfactants ensures efficacy in reducing bacterial contamination, managing exudate, and promoting tissue regeneration. SilverStream is the one solution for complete recovery, revolutionizing wound care and SSI prevention.
Diabetic Ulcers Clinical Evidence
Discover how SilverStream demonstrates effectiveness in managing DU, promoting healing, reducing infection risk, removing non-viable tissue, minimizing dressing frequency, and improving patient outcomes.
Pressure Ulcers Clinical Evidence
Learn how SilverStream supports the healing of pressure ulcers by debriding necrotic tissue, reducing infection risks, minimizing dressing frequency, and enhancing patient comfort with proven clinical outcomes.
Venous/Arterial Ulcers Clinical Evidence
Discover how SilverStream promotes the healing of venous and arterial ulcers by targeting biofilm, reducing infection risks, and supporting the journey to full closure with clinically proven results in home care treatment.
The Synergy Behind SilverStream Technology
Learn how SilverStream’s advanced technology disrupts biofilm, controls infection, and delivers exceptional antimicrobial protection for optimal wound healing
Trauma Cases and Orthopedics
Discover how SilverStream supports effective wound management in trauma and orthopedic cases, including open fractures, external fixators, and osteomyelitis, by reducing infection risks, promoting healing, and enhancing patient outcomes.
Burns and Plastics Clinical Evidence
Explore how SilverStream supports burns and plastic surgery care, including pediatric burns, grafting, and reconstruction, by promoting healing, reducing infection risks (Pseudomonas, Staphylococcus aureus), and improving outcomes.
Post Surgical Site Infections (Post SSI)
Learn how SilverStream effectively manages post-surgical site infections, including cases with implants, MRSA biofilm, and other antibiotic-resistant bacteria, reducing the need for re-surgery and improving patient recovery outcomes.
Caution: This video contains clinical case studies and visuals of severe wounds, which may be sensitive or unsettling to some viewers. Viewer discretion is advised.
Diabetic Ulcers Clinical Evidence
Discover how SilverStream demonstrates effectiveness in managing DU, promoting healing, reducing infection risk, removing non-viable tissue, minimizing dressing frequency, and improving patient outcomes.
Pressure Ulcers Clinical Evidence
Learn how SilverStream supports the healing of pressure ulcers by debriding necrotic tissue, reducing infection risks, minimizing dressing frequency, and enhancing patient comfort with proven clinical outcomes.
Venous/Arterial Ulcers Clinical Evidence
Discover how SilverStream promotes the healing of venous and arterial ulcers by targeting biofilm, reducing infection risks, and supporting the journey to full closure with clinically proven results in home care treatment.
Trauma Cases and Orthopedics
Discover how SilverStream supports effective wound management in trauma and orthopedic cases, including open fractures, external fixators, and osteomyelitis, by reducing infection risks, promoting healing, and enhancing patient outcomes.
Burns and Plastics Clinical Evidence
Explore how SilverStream supports burns and plastic surgery care, including pediatric burns, grafting, and reconstruction, by promoting healing, reducing infection risks (Pseudomonas, Staphylococcus aureus), and improving outcomes.
Post Surgical Site Infections (Post SSI)
Learn how SilverStream effectively manages post-surgical site infections, including cases with implants, MRSA biofilm, and other antibiotic-resistant bacteria, reducing the need for re-surgery and improving patient recovery outcomes.