SilverStream Solution

SilverStream® | Solution for Chronic Wounds & Diabetic Foot Ulcer

Supplied in 100mL, 250mL or 500mL bottles

SilverStream® Solution: Silver Nitrate Solution for Diabetic Foot & Chronic Wound Ulcer Care 

Advanced Wound Management

SilverStream® Solution is a highly effective, professional-grade wound management solution. It is clinically indicated for the cleansing, moisturizing, and soothing of a broad spectrum of acute and chronic conditions, performing multiple functions to accelerate the physiological healing process:

  • Diabetic Foot Ulcers (DFU): Accelerates wound closure and manages infection in high-risk patients with diabetic wounds.
  • Pressure Ulcers (Stage I-IV): Facilitates the continuous debridement of bed sores and prevents the progression of deep tissue injury.
  • Chronic & Non-Healing Wounds: Effectively manages Stasis (Venous) Ulcers and other chronic sores that have stalled in the inflammatory phase.
  • Surgical Wounds: Promotes rapid granulation and provides superior management for Post-Surgical Ulcers and incisions.
  • Burns: Specially formulated for 1st & 2nd-degree burns, ensuring the area remains moist and protected from microbial contamination.
  • Minor Skin Trauma: Provides immediate care for Cuts, Abrasions, and Minor Skin Irritations, soothing the tissue while preventing infection.

SilverStream® contains Antimicrobial Silver Ions for the Treatment of chronic and non-healing wounds.

SilverStream’s innovative synergetic formulation ensures an effective anti-microbial preservative, as well as a biofilm destruction function. SilverStream Solutions:

  • Is Non-toxic and Non-irritating
  • Contains no Steroids or Antibiotics
  • Contains no Alcohol or Iodine
  • Won’t harm healthy tissue
  • Is Environmentally friendly – no special disposal required

The clear, colorless solution is protected from microbial contamination by a low concentration of Ionic Silver.

SilverStream®: Versatile Wound Treatment Cycle

Treatment CategoryClinical Focus & KeywordsSilverStream® Application & Benefit
Diabetic UlcersDiabetic foot ulcer, diabetic woundAccelerates closure in high-risk patients; manages infection in diabetic wound ulcers.
Venous UlcersStasis ulcers, non-healing soresEffectively manages stasis/venous ulcers by disrupting persistent bacterial biofilms.
Pressure UlcersBed sores, Stage I-IV ulcersFacilitates continuous debridement and reduces localized inflammation in chronic pressure sores.
Trauma CasesLacerations, deep woundsCleanses and protects large trauma sites from microbial contamination during the advanced wound healing process.
Prevention of UlcersEarly stage protectionMaintains skin integrity and physiological pH to prevent the breakdown of vulnerable tissue.
Burns1st & 2nd-degree burnsSoothes the area, reduces pain, and promotes regeneration without harming healthy tissue.
Acute WoundsScrapes, punctures, recent injuriesProvides a sterile, antimicrobial environment to prevent acute injuries from becoming chronic.
Post-Surgical WoundPost-surgical ulcers, incisionsPromotes rapid granulation and reduces recovery time for post-operative sites.
Cosmetic ProceduresSkin rejuvenation recoveryImproves the look and appearance of skin while managing post-procedure inflammation.
Cuts & AbrasionsMinor skin irritationCleans, moisturizes, and soothes minor trauma with a clear, non-staining antimicrobial solution.

This weekend, my 16‑year‑old son burned his face applying salicylic acid. It quickly reddened and swelled and looked infected, his aunt—an RNP—suspected impetigo. But with dermatologist offices closed and this being on his face, her prescription plan was a risk we felt uncomfortable taking. That’s when his father suggested SilverStream. He said if it's a bacterial infection or a fungus, SilverStream should stop both from replicating and one of its main uses is burn healing. So it should address all 3 problems, with that advice we chose to use SilverStream instead of the prescription impetigo cream. We figured we would try this until the dermatologist offices open on Monday. The results blew our minds! These are images of before and 4hrs after applying SilverStream, then 24hrs and 48hrs after. All we used was SilverStream and sterile gauze. Thank you GWHP for making this amazing product available in the states! Sincerely an extremely happy mom/customer from Covina, CA

Parent in Covina, CA

Why SilverStream® Outperforms Traditional Care:

Antimicrobial action: Silver-based wound care is proven to reduce infection and support healing in burns and ulcers.

  • Antimicrobial Action: Unlike standard cleansers, silver-based wound care is clinically proven to reduce infection and support healing in high-risk burns and ulcers.
  • Gentle on Tissue: Traditional treatments like silver sulfadiazine may delay epithelialization; SilverStream® is specifically designed to promote regeneration without inhibiting cellular growth.
  • Convenience and Comfort: Its odorless and pain-relieving properties make it a superior choice for home-health agencies and patients when medical offices are closed.

Our unique one-step process performs the following functions on all applications and thus accelerates the healing process while keeping the wound free of infection.

Reactivates Prompt Healing
Provides Continuous Debridement, Reduces Inflammation, Promotes Blood Circulation, & Stimulates Tissue Granulation
Promotes & Balances Moisture
Penetrates Deeper into the Wound Surface, Facilitates the Absorption & Reduction of Exudates, Prevents Maceration
Strong Anti-Microbial Efficacy
Destroys Biofilm, Prevents Re-Infection; No Bacterial Resistance, Inhibits the growth of Bacteria, Yeast, and Fungi
Soothing Effect during the Treatment
Reduces Pain & Eliminates Odor, Improves Look & Appearance of Skin
Proven Efficacy and Safety

Maintains Non-toxic and Non-cytotoxic, No Argyria, No Environment Coloring and No Staining

Mechanism of Action

IngredientActionDescription
Ag NO3Preservative & Anti-microbial agentIonic silver kills on contact and inhibits the growth of bacteria, yeast, and fungi
MentholPenetration enhancer, Growth promoter, Pain reliever, Odor fighterEnhances ionic silver antimicrobial activities and fights wound odor
Promotes granulation tissue growth by vasodilatation
Tween 20Surfactant and DetergentEnhances solution penetration into the biofilm
Acts as wound cleansing detergent
GlycerolA hypertonic aqueous solution that prevents macerations
Soothing agent
Aids mechanical removal of exudates and microorganisms
Creates Hydrogel function by absorbing water molecules
Tris BufferBuffered neutral pHBiocompatible to physiological pH

How It Works

SilverStream® is a patented wound management solution, that combines a low concentration of silver ions, menthol, and glycerol plus a surfactant, dissolved in a hypertonic solution.

SilverStream® specialized synergistic combination of silver ions and menthol reduces the concentration level of the silver ions – to well below the cytotoxic threshold.

The high concentration of the hygroscopic glycerol provides hydrogel effects.

Gentle Patient Care & Ease of Use. No Coloring, Staining or Argyria, Eliminates Odor, Reduces Pain, Prevents Maceration, and Reduces the Treatment Period.

Accelerates Wound Healing

Reduces Treatment Period

Long Term Clinical Efficiency

Reduce overall Treatment Costs

What makes SilverStream far more effective in closing wounds more rapidly than other formulations?

The unique combination of SilverStream’s ingredients and their non-toxic, non-cytotoxic properties, stimulate the growth of granulation tissue. SilverStream prevents maceration and facilitates the absorption and reduction of exudates while keeping the wound moist for longer periods (due to the hydrogel property) thus accelerating the wound healing process.

1. Provides Continuous Debridement, Reduces Inflammation, Promotes Blood Circulation, & Stimulates Tissue Granulation.
2. Promotes & Balances Moisture, Penetrates Deeper into the Wound Surface, Facilitates the Absorption & Reduction of Exudates, Prevents Maceration.
3. Destroys Biofilm, Prevents Re-Infection; No Bacterial Resistance, Inhibits the Growth of Bacteria, Yeast, and Fungi.
4. Soothing Effect during the Treatment, Reduces Pain & Eliminates Odor, Improves Look & Appearance of Skin.
5. Non toxic, Non cytotoxic, No Argyria, No Coloring & No Staining.

Why does a low concentration of silver ions effectively function as an anti-microbial preservative in the presence of menthol?

During the development of SilverStream, we discovered that there is a synergic effect between the silver ions and menthol, which enhances the penetration of silver ions through the bacteria cell wall into the bacteria. This enabled us to ensure that the concentration of silver ions remains below the toxic and cytotoxic levels.

Why does SilverStream have Hydrogel properties? How do such properties assist in chronic wound management?

The presence of a high concentration of hygroscopic glycerol gives SilverStream its hydrogel properties due to the reduction of water activity by the glycerol, preventing the growth of micro-organisms. These hydrogel properties also help SilverStream to keep the wound moist for a longer time.

What is the reason for the pain relief provided by SilverStream?

Glycerol and menthol contribute to the pain relief effect of SilverStream, as well as accelerated Wound Healing induced by the solution.

Easy to Apply

Step 1:

Open the cap, insert syringe with needle into the bottle and draw up the quantity of SilverStream® solution as advised by the Medical Practitioner.

Step 2:

Rinse, by spraying the SilverStream® solution on the
wound. DO NOT INJECT (The needle should not touch the wound).

Step 3:

Wet a sterile cotton gauze with SilverStream® solution.

Step 4:

Place the wet gauze on the wound and apply a secondary non-antimicrobial occlusive dressing as directed by the Medical Practitioner.

Step 5:

Before removal of the gauze/dressing or sponge, moisten with SilverStream® solution for easier removal.

SilverStream® can also be applied via a spray bottle, irrigation or lavage system.

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