Global WholeHealth Partners

Glossary

Abscess

Accumulation of pus enclosed anywhere in the body.

Abrasion

Wearing away through some mechanical process such as friction or trauma.

Angiogenesis

The process of producing blood vessels during the granulation phase of wound healing.

Autolysis

The process of breakdown down of dead tissue or devitalized tissue with the use of enzymes.

Atrophie Blanche

Atrophic (thin) skin with ivory-white, depressed, discolored tissue with red dots of the dermal capillaries, typically seen around the ankles. May arise within the fibrotic area of lipodermatosclerosis and doesn’t represent a healed ulcer.

Bioburden

Dead cells and fluid that collects between dressing changes and needs cleaning off the wound bed to allow healing. The burden caused by bacteria in the wound competing for oxygen and nutrients.

Biofilm

A biofilm is an assemblage of surface-associated microbial cells that is enclosed in an extracellular polymeric substance matrix.

A wound biofilm is formed when certain microorganisms, mostly pathogenic bacteria, adhere to the wound surface. Biofilms are formed by a three-dimensional (3D) matrix that provides protection and cohesion for bacteria growing in wound sites. Biofilm gives the additional resistance power to bacteria which makes them to not only tolerate harsh conditions but also resistant to antibiotics which lead to the emergence of bad bugs infections like multi drug resistant, extensively drug resistant and totally drug resistant bacteria.

Blanching

The reddened area that becomes white with pressure applied.

Cellulitis

Inflammation or infection of skin cells that cause redness, heat, pain and edema.

Charcot

A condition from diabetes where the bones in the feet dislocate, deform or fracture cause the bottom of the foot to have the appearance of the hull of the boat related to the arch collapsing.

Claudication

Cramping leg pain with exercise, such as walking, from ischemia of the leg muscle groups. Results from proximal narrowing of the arterial tree associated with PAD. Exercising muscles need more oxygen than resting muscles. In persons with PAD, these muscles don’t get the extra oxygenated blood that they need, leading to tissue ischemia and pain. Claudication resolves with rest.

Clean wound

Free of devitalized tissue, purulent drainage and debris.

Collagen

The protein that is the main component of many major parts of the body and wound healing

Colonized

Presence of replicating bacteria in or around the wound bed; no local or systemic effects. No antibiotics please.

Contamination

Introduction of non-replicating organisms into wound.

Contraction

Bringing together of wound edges causing the wound size to become smaller. It is important to measure wounds to show healing or deterioration over time.

Critical colonization

Organisms on surface of wound, but in high enough numbers that microbial load has stalled healing process.

Communicating veins

Veins that connect to other veins within the same anatomic plane. For example, a vein that connects the superficial greater saphenous vein medially to the superficial lesser saphenous vein laterally.

Dead space

Defect or cavity that can result in abscess formation.

Debridement

Removal of foreign material and devitalized or contaminated tissue from a wound until healthy tissue is exposed.

Dehiscence

Separation of wound edges.

Denudement

Loss of epidermis.

Detrition

The mechanical process of wearing away by friction.

Epibole

Non-healing wounds with closed, rolled wound edges. Two layers of epidermis have rolled down to cover lower layers. Halts the migration of epithelial cells into the wound bed.

Epidermis

Outermost layer of skin.

Erode

Loss of epidermis.

Erythema

Increased redness, often the first sign of infection. Redness of the skin cause by vasodilation.

Eschar

Necrotic tissue, usually black or brown. Can be hard and dry or soft and boggy; thick, leathery black crust. Non-viable tissue that is colonized with bacteria.

Excoration

Linear scratches on skin.

Exudate

Non-healing wounds with closed, rolled wound edges. Two layers of epidermis have rolled down to cover lower layers. Halts the migration of epithelial cells into the wound bed.

Fibrin

Non-healing wounds with closed, rolled wound edges. Two layers of epidermis have rolled down to cover lower layers. Halts the migration of epithelial cells into the wound bed.

Fascia

Non-healing wounds with closed, rolled wound edges. Two layers of epidermis have rolled down to cover lower layers. Halts the migration of epithelial cells into the wound bed.

Fibroblast

An important cell used in wound healing.

Friable tissue

The tissue that bleeds easily and can indicate infection.

Friction

Rubbing that causes mechanical trauma to the skin.

Full thickness

Tissue damage extends through dermis into subcutaneous tissue. Can include muscle, fascia and bone.

Granulation tissue

Formation of red, healthy connective tissue with good blood flow in a full thickness wound that will continue to heal. Can appear as red and cobblestoned.

Growth factors

Proteins that are used to bring cells to an area as well as create other proteins used in wound healing.

Hemosiderin staining

Permanent brown staining to lower leg to indicate venous disease. It is caused by the release of iron from disintegrate red blood cells. Classic sign of venous stasis changes. Discoloration of soft tissue caused by localized erythema and superficial erosions.

Hydrophilic

Attracting moisture.

Induration

An abnormal firmness or thickness with definite margins palpated under skin, often surrounding a wound or localized injury.

Infected

Invasion of organisms into tissue and systemic response noted. Overgrowth of microorganisms in sufficient quantities to overwhelm the body’s defenses. Start antibiotics. Hint: Chronic wounds may not exhibit classic signs of infection. Look for increased pain or drainage, odor and delayed healing.

Interigo

A mild inflammatory process caused by moisture and skin-to-skin friction. Often seen in skin folds and characterized by the breakdown of red blood cells resulting in hyper-pigmentation of the skin.

Intermittent claudication

Pain related to poor or compromised blood supply. The pain is acute when walking and decreases with rest. Increase in pain often happens with leg elevation.

Ischemia

The loss or deficiency of blood to an area.

Lesion

Broad term referring to wounds and sores.

Lipodermatosclerosis

A skin and connective tissue disease that is inflammation of the fat layer of the epidermis. A change in the skin of the lower legs, resembling an inverted bowling pin or champagne bottle, common in patients with chronic venous insufficiency (CVI). A constricted area of adherent fibrotic subcutaneous tissue and skin. More proximal to his narrowing is a swollen area of the leg caused by CVI and edema.

Maceration

The whiteness and loss of intact skin around wound margins as a result of dressing not able to pull or control excess fluid. Skin damage caused by moisture. Softening of tissue by soaking in fluids (can look like “dishpan hands”).

Necrotic tissue

Dead tissue that found in the wound bed as a result of loss of blood flow. This tissue is usually black or brown and leathery.

Oedema

Swelling.

Off-loading

Taking the weight off in order to increase blood flow. Without off-loading, suspected deep tissue injury will occur or chronic wound.

Osteomyelitis

Inflammation of the bone; bone infection.

Partial thickness

Loss of epidermis and possibly part of the dermis. Damage does not extend through dermis. Very painful. These wounds heal by re-epithelialisation. Hint: Look for hair follicles.

Perforator veins

Veins that allow communication between the superficial venous system and deep venous system of the legs as they pass through the muscular fascia. May be above or below the knee.

Peri-wound

The tissue surrounding the wound. This tissue needs to be assessed for warmth, color or signs of discoloration, to indicate other problems. Example: By assessing the leg surrounding the wound, can indicate venous insufficiency.

Pink tissue

Epithelial tissue can be shiny pink or white tissue.

Pus

Thick fluid composed of leukocytes, bacteria and cellular debris.

Reticular veins

Bluish, dilated subdermal veins 1 to 3mm in diameter.

Shear

Sliding of skin over subcutaneous tissues and bones causing a kink in cutaneous capillaries which may lead to ischemia.

Sinus tract

Tunneling that connects two body structures.

Slough

Necrotic tissue, usually soft and yellow (but may look grey) that can adhere to the wound bed.

Strip

Removal of epidermis by mechanical means, usually tape.

Telangiectasia

 Dilated intradermal veins less than 1mm in diameter.

Tunneling

Destruction of tissue around the infected area; a wound that has channels extending from the central injury into the surrounding tissue, such as muscle and skin. These tunnels inhibit the wound’s healing.

Ulcer

Loss of epidermis/dermis or mucous membrane with definite margins.

Undermining

Area of tissue destruction extending under the skin along the periphery of the wound. The wound is spread out underneath the skin that surrounds the visible part of the wound. The wound is bigger than what it appears at first glance.

Unstageable Pressure Ulcer

Covered with eschar or slough which prohibits complete assessment of the wound.

Varicose veins

Dilated, tortuous subcutaneous veins of 3mm or more in diameter.

Wound

A break in the integrity of the skin; an injury to the body which causes a disruption of the normal continuity of the body structures.

Wound margin

Rim or border of a wound.

Exudate

Fluid from the wound that can be serous, sanguineous or purulent.

MMPS

Matrix metalloproteinases (MMPs) are a group of endopeptidases that play a vital role in the restoration of damaged skin.

SSI

A surgical site infection (SSI) is an infection that occurs after surgery in the part of the body where the surgery took place.

Stage 1 Pressure Ulcer

An observable pressure-related alteration of intact skin whose indicators, as compared to adjacent or opposite areas on the body, may include changes in one or more of the following: skin temperature (warmth or coolness), tissue consistency (firm or boggy feel), and/or sensation (pain, itching). The ulcer appears as a defined area of persistent redness in lightly pigmented skin, whereas in darker skin tones, the ulcer may appear with persistent red, blue or purple hues.

Stage 2 Pressure Ulcer

Involves the epidermis, dermis or both. It is a superficial wound and may present as an abrasion, blister or shallow crater.

Stage 3 Pressure Ulcer

Involves subcutaneous tissue that may extend down to but not through underlying fascia. It may present as a deep crater with or without undermining of tissue.

Stage 4 Pressure Ulcer

Involves muscle, bone, or supporting structures.
Undermining or sinus tract may also be present.