Stimulation of Quiescent and Mildly Infected Diabetic Foot and Venous Ulcers using a Wound Optimizing Irrigant

Adam Landsman, DPM, PhD, FACFAS. Chief, Division of Podiatric Surgery, Cambridge Health Alliance Assistant Professor of Surgery, Harvard Medical School 1493 Cambridge St., Cambridge, MA 02139.

Submitted for publication to the International Wound Journal

Abstract :

This study represents the first observational analysis for the treatment of mildly infected, non-progressive diabetic foot ulcers and venous leg ulcers treated with SilverStream®, a wound irrigant used to stimulate healing by reducing bacteria count, disrupting biofilms, eliminating odor, and stimulating angiogenesis.
Data collected from 39 wounds at 8 independent sites was reviewed to determine the change in overall appearance and conditions following either daily or weekly treatment with SilverStream over a period of 5 weeks.

The wounds demonstrated significant decreases in discharge, odor and necrotic or non-viable tissue. 21.5% of the wounds closed completely in 5 weeks or less, and the average decrease in wound size was 59.08% in wounds that were initially between 1 and 15 cm2. There was a 19% increase in granulation tissue and a 9% decrease in fibrotic and non-viable tissue during the same 5 week period.
This preliminary data strongly suggests that quiescent wounds can be stimulated to begin healing with this wound irrigant. SilverStream fills a unique niche in the treatment of diabetic foot ulcers and venous leg ulcers by optimizing conditions necessary for these wounds to close.

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